| SEATTLE MARINERS 2000 SCHEDULE | |||
| Date | Day | Opponent | Game Time |
| April 3 | Monday | vs. Red Sox | 1:35 PM |
| April 4 | Tuesday | vs. Red Sox | 7:05 PM |
| April 5 | Wednesday | vs. Red Sox | 7:35 PM |
| April 7 | Friday | vs. Yankees | 7:05 PM |
| April 8 | Saturday | vs. Yankees | 1:05 PM |
| April 9 | Sunday | vs. Yankees | 12:35 PM |
| April 10 | Monday | at Tigers | TBA |
| April 12 | Wednesday | at Tigers | 4:05 PM |
| April 13 | Thursday | at Tigers | 4:05 PM |
| April 14 | Friday | at Blue Jays | 4:05 PM |
| April 15 | Saturday | at Blue Jays | 1:05 PM |
| April 16 | Sunday | at Blue Jays | 10:05 AM |
| April 17 | Monday | at White Sox | 5:05 PM |
| April 18 | Tuesday | at White Sox | 5:05 PM |
| April 19 | Wednesday | at White Sox | 11:05 AM |
| April 21 | Friday | vs. Royals | 7:05 PM |
| April 22 | Saturday | vs. Royals | 1:05 PM |
| April 23 | Sunday | vs. Royals | 1:35 PM |
| April 24 | Monday | vs. Indians | 7:05 PM |
| April 25 | Tuesday | vs. Indians | 7:05 PM |
| April 26 | Wednesday | vs. Indians | 3:35 PM |
| April 28 | Friday | at Royals | 5:05 PM |
| April 29 | Saturday | at Royals | 5:05 PM |
| April 30 | Sunday | at Royals | 11:05 AM |
| May 1 | Monday | at Twins | 5:05 PM |
| May 2 | Tuesday | at Twins | 5:05 PM |
| May 3 | Wednesday | at Twins | 5:05 PM |
| May 5 | Friday | vs. Angels | 7:05 PM |
| May 6 | Saturday | vs. Angels | 1:05 PM |
| May 7 | Sunday | vs. Angels | 1:35 PM |
| May 8 | Monday | at Rangers | 5:05 PM |
| May 9 | Tuesday | at Rangers | 5:05 PM |
| May 10 | Wednesday | at Rangers | 12:05 PM |
| May 11 | Thursday | at Athletics | 7:05 PM |
| May 12 | Friday | at Athletics | 7:05 PM |
| May 13 | Saturday | at Athletics | 1:05 PM |
| May 14 | Sunday | at Athletics | 1:05 PM |
| May 15 | Monday | vs. Twins | 7:05 PM |
| May 16 | Tuesday | vs. Twins | 7:05 PM |
| May 17 | Wednesday | vs. Twins | 7:35 PM |
| May 19 | Friday | vs. Devil Rays | 7:05 PM |
| May 20 | Saturday | vs. Devil Rays | 1:05 PM |
| May 21 | Sunday | vs. Devil Rays | 1:35 PM |
| May 23 | Tuesday | at Orioles | 4:05 PM |
| May 24 | Wednesday | at Orioles | 4:05 PM |
| May 25 | Thursday | at Orioles | 4:05 PM |
| May 26 | Friday | at Devil Rays | 4:15 PM |
| May 27 | Saturday | at Devil Rays | 1:15 PM |
| May 28 | Sunday | at Devil Rays | 10:15 AM |
| May 29 | Monday | vs. White Sox | 6:05 PM |
| May 30 | Tuesday | vs. White Sox | 7:05 PM |
| May 31 | Wednesday | vs. White Sox | 3:35 PM |
| June 2 | Friday | vs. Padres | 7:05 PM |
| June 3 | Saturday | vs. Padres | 6:05 PM |
| June 4 | Sunday | vs. Padres | 1:35 PM |
| June 5 | Monday | vs. Rockies | 7:05 PM |
| June 6 | Tuesday | vs. Rockies | 7:05 PM |
| June 7 | Wednesday | vs. Rockies | 7:05 PM |
| June 9 | Friday | at Giants | TBA |
| June 10 | Saturday | at Giants | TBA |
| June 11 | Sunday | at Giants | TBA |
| June 12 | Monday | at Royals | 5:05 PM |
| June 13 | Tuesday | at Royals | 5:05 PM |
| June 14 | Wednesday | at Royals | 11:05 AM |
| June 16 | Friday | at Twins | 5:05 PM |
| June 17 | Saturday | at Twins | 4:05 PM |
| June 18 | Sunday | at Twins | 11:05 AM |
| June 19 | Monday | vs. Devil Rays | 7:05 PM |
| June 20 | Tuesday | vs. Devil Rays | 7:05 PM |
| June 21 | Wednesday | vs. Devil Rays | 7:35 PM |
| June 22 | Thursday | vs. Orioles | 7:05 PM |
| June 23 | Friday | vs. Orioles | 7:05 PM |
| June 24 | Saturday | vs. Orioles | 1:05 PM |
| June 25 | Sunday | vs. Orioles | 1:35 PM |
| June 27 | Tuesday | vs. Angels | 7:05 PM |
| June 28 | Wednesday | vs. Angels | 7:35 PM |
| June 29 | Thursday | vs. Angels | 1:05 PM |
| June 30 | Friday | at Rangers | 5:35 PM |
| July 1 | Saturday | at Rangers | 5:35 PM |
| July 2 | Sunday | at Rangers | 5:05 PM |
| July 3 | Monday | at Angels | 7:05 PM |
| July 4 | Tuesday | at Angels | 7:05 PM |
| July 5 | Wednesday | at Angels | 7:35 PM |
| July 6 | Thursday | at Angels | 7:05 PM |
| July 7 | Friday | vs. Dodgers | 7:05 PM |
| July 8 | Saturday | vs. Dodgers | 1:05 PM |
| July 9 | Sunday | vs. Dodgers | 1:35 PM |
| July 13 | Thursday | at Padres | 2:05 PM |
| July 14 | Friday | at Padres | 7:05 PM |
| July 15 | Saturday | at Padres | 7:05 PM |
| July 16 | Sunday | at Diamondbacks | 1:35 PM |
| July 17 | Monday | at Diamondbacks | 7:05 PM |
| July 18 | Tuesday | at Diamondbacks | 7:05 PM |
| July 19 | Wednesday | at Athletics | 7:05 PM |
| July 20 | Thursday | at Athletics | 12:35 PM |
| July 21 | Friday | vs. Rangers | 7:05 PM |
| July 22 | Saturday | vs. Rangers | 1:05 PM |
| July 23 | Sunday | vs. Rangers | 1:35 PM |
| July 24 | Monday | vs. Athletics | 7:05 PM |
| July 25 | Tuesday | vs. Athletics | 7:05 PM |
| July 26 | Wednesday | vs. Athletics | 7:35 PM |
| July 27 | Thursday | vs. Blue Jays | 7:05 PM |
| July 28 | Friday | vs. Blue Jays | 7:05 PM |
| July 29 | Saturday | vs. Blue Jays | 6:05 PM |
| July 30 | Sunday | vs. Blue Jays | 1:35 PM |
| July 31 | Monday | vs. Red Sox | 7:05 PM |
| August 1 | Tuesday | vs. Red Sox | 7:05 PM |
| August 2 | Wednesday | vs. Red Sox | 7:35 PM |
| August 4 | Friday | at Yankees | 4:35 PM |
| August 5 | Saturday | at Yankees | 10:35 AM |
| August 6 | Sunday | at Yankees | 10:35 AM |
| August 7 | Monday | at Yankees | 4:35 PM |
| August 8 | Tuesday | at White Sox | 5:05 PM |
| August 9 | Wednesday | at White Sox | 5:05 PM |
| August 10 | Thursday | at White Sox | 11:05 AM |
| August 11 | Friday | vs. Indians | 7:05 PM |
| August 12 | Saturday | vs. Indians | 6:05 PM |
| August 13 | Sunday | vs. Indians | 1:35 PM |
| August 14 | Monday | vs. Tigers | 7:05 PM |
| August 15 | Tuesday | vs. Tigers | 7:05 PM |
| August 16 | Wednesday | vs. Tigers | 3:35 PM |
| August 18 | Friday | at Indians | 4:05 PM |
| August 19 | Saturday | at Indians | 4:05 PM |
| August 20 | Sunday | at Indians | 10:05 AM |
| August 22 | Tuesday | at Tigers | 4:05 PM |
| August 23 | Wednesday | at Tigers | 4:05 PM |
| August 24 | Thursday | at Tigers | 10:05 AM |
| August 25 | Friday | vs. White Sox | 7:05 PM |
| August 26 | Saturday | vs. White Sox | 6:05 PM |
| August 27 | Sunday | vs. White Sox | 1:35 PM |
| August 28 | Monday | vs. Yankees | 7:05 PM |
| August 29 | Tuesday | vs. Yankees | 7:05 PM |
| August 30 | Wednesday | vs. Yankees | 7:35 PM |
| September 1 | Friday | at Red Sox | 4:05 PM |
| September 2 | Saturday | at Red Sox | 10:05 AM |
| September 3 | Sunday | at Red Sox | 10:05 AM |
| September 4 | Monday | at Red Sox | 10:05 AM |
| September 5 | Tuesday | at Blue Jays | 4:05 PM |
| September 6 | Wednesday | at Blue Jays | 4:05 PM |
| September 7 | Thursday | at Blue Jays | 4:05 PM |
| September 8 | Friday | vs. Twins | 7:05 PM |
| September 9 | Saturday | vs. Twins | 6:05 PM |
| September 10 | Sunday | vs. Twins | 1:35 PM |
| September 11 | Monday | vs. Royals | 7:05 PM |
| September 12 | Tuesday | vs. Royals | 7:05 PM |
| September 13 | Wednesday | vs. Royals | 7:35 PM |
| September 15 | Friday | at Orioles | 4:05 PM |
| September 16 | Saturday | at Orioles | 4:05 PM |
| September 17 | Sunday | at Orioles | 10:35 AM |
| September 18 | Monday | at Devil Rays | 4:15 PM |
| September 19 | Tuesday | at Devil Rays | 4:15 PM |
| September 20 | Wednesday | at Devil Rays | 4:15 PM |
| September 21 | Thursday | vs. Athletics | 7:05 PM |
| September 22 | Friday | vs. Athletics | 7:05 PM |
| September 23 | Saturday | vs. Athletics | TBA |
| September 24 | Sunday | vs. Athletics | 1:35 PM |
| September 26 | Tuesday | vs. Rangers | 7:05 PM |
| September 27 | Wednesday | vs. Rangers | 7:35 PM |
| September 28 | Thursday | vs. Rangers | 3:35 PM |
| September 29 | Friday | at Angels | 7:05 PM |
| September 30 | Saturday | at Angels | 7:05 PM |
| October 1 | Sunday | at Angels | 1:05 PM |
| All times Pacific. Subject to change | |||